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---
license: mit
---
**Base model:** [westlake-repl/SaProt_650M_AF2](https://huggingface.co/westlake-repl/SaProt_650M_AF2)
**Task type:** protein-level regression
Label measuring the most extreme circumstances in which protein maintains its fold above a concentration threshold (a proxy for intrinsic stability).
**Dataset:** [SaProtHub/Dataset-Stability-TAPE](https://huggingface.co/datasets/SaProtHub/Dataset-Stability-TAPE)
**Model input type:** Amino acid sequence
**Performance (on test set):** 0.825 Spearman's ρ
**LoRA config:**
- **r:** 8
- **lora_dropout:** 0.1
- **lora_alpha:** 8
- **target_modules:** ["query", "key", "value", "intermediate.dense", "output.dense"]
- **modules_to_save:** ["classifier"]
**Training config:**
- **optimizer:**
- **class:** AdamW
- **betas:** (0.9, 0.98)
- **weight_decay:** 0.01
- **learning rate:** 1e-4
- **epoch:** 50
- **batch size:** 64
- **precision:** 16-mixed |