---
license: mit
---

**Base model:** [westlake-repl/SaProt_650M_AF2](https://huggingface.co/westlake-repl/SaProt_650M_AF2)

**Task type:** protein-level regression

Label measuring the most extreme circumstances in which protein maintains its fold above a concentration threshold (a proxy for intrinsic stability).

**Dataset:** [SaProtHub/Dataset-Stability-TAPE](https://huggingface.co/datasets/SaProtHub/Dataset-Stability-TAPE)

**Model input type:** Amino acid sequence

**Performance (on test set):** 0.825 Spearman's ρ

**LoRA config:**
- **r:** 8
- **lora_dropout:** 0.1
- **lora_alpha:** 8
- **target_modules:** ["query", "key", "value", "intermediate.dense", "output.dense"]
- **modules_to_save:** ["classifier"]

**Training config:**

- **optimizer:**
  - **class:** AdamW
  - **betas:** (0.9, 0.98)
  - **weight_decay:** 0.01
- **learning rate:** 1e-4
- **epoch:** 50
- **batch size:** 64
- **precision:** 16-mixed