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license: mit |
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**Base model:** [westlake-repl/SaProt_650M_AF2](https://huggingface.co/westlake-repl/SaProt_650M_AF2) |
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**Task type:** protein-level regression |
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Label measuring the most extreme circumstances in which protein maintains its fold above a concentration threshold (a proxy for intrinsic stability). |
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**Dataset:** [SaProtHub/Dataset-Stability-TAPE](https://huggingface.co/datasets/SaProtHub/Dataset-Stability-TAPE) |
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**Model input type:** Amino acid sequence |
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**Performance (on test set):** 0.825 Spearman's ρ |
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**LoRA config:** |
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- **r:** 8 |
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- **lora_dropout:** 0.1 |
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- **lora_alpha:** 8 |
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- **target_modules:** ["query", "key", "value", "intermediate.dense", "output.dense"] |
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- **modules_to_save:** ["classifier"] |
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**Training config:** |
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- **optimizer:** |
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- **class:** AdamW |
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- **betas:** (0.9, 0.98) |
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- **weight_decay:** 0.01 |
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- **learning rate:** 1e-4 |
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- **epoch:** 50 |
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- **batch size:** 64 |
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- **precision:** 16-mixed |